Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671776 | 0.91 | ALDH1A1 (0.46) | VCAM1SMN1; SMN2ALDH1A1NPSR1MCOLN3 | |
| SCHEMBL11508791 | 0.84 | MCOLN3 (0.47) | VCAM1SMN1; SMN2ALDH1A1NPSR1MCOLN3 | |
| SCHEMBL11510273 | 0.79 | VCAM1 (0.42) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL11670509 | 0.76 | ALDH1A1 (0.47) | VCAM1SMN1; SMN2POLBALDH1A1KMT2A | |
| SCHEMBL10687962 | 0.75 | ALDH1A1 (0.47) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL11670581 | 0.72 | VCAM1 (0.37) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL9305533 | 0.72 | HTT (0.54) | VCAM1SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL3844818 | 0.70 | VCAM1 (0.46) | VCAM1SMN1; SMN2ALDH1A1NPSR1KMT2A | |
| SCHEMBL11596703 | 0.70 | VCAM1 (0.44) | VCAM1SMN1; SMN2POLBALDH1A1NPSR1 | |
| SCHEMBL11508081 | 0.70 | ALDH1A1 (0.43) | VCAM1SMN1; SMN2ALDH1A1NPSR1MCOLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041073-A | 3,4,5-Trichloro-N,N-di(loweralkyl)-2-(mercapto) benzenesulfonamides | THE DOW CHEMICAL COMPANY (US) | 1977-08-09 | — | — | US | disclosed |
| US-4035407-A | 3,4,5-Trichloro-N,N-di(loweralkyl)-2-thiomethylthiocyanato)benzene-sulfonamides | THE DOW CHEMICAL COMPANY (US) | 1977-07-12 | — | — | US | disclosed |