SCHEMBL11671985

SCHEMBL11671985

CCN(CCOCCOC(=O)Oc1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 4/20 0.44
TSHR P16473 4/20 0.44
CHRM2 P08172 3/20 0.44
CHRM1 P11229 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
HTT P42858 2/20 0.44
LMNA P02545 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2D6 P10635 2/20 0.44
THRB P10828 2/20 0.44
SLC22A1 O15245 1/20 0.44
PRCP P42785 1/20 0.44
TMEM97 Q5BJF2 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11148002 0.92 ATM (0.42) ALDH1A1TSHRCHRM2CHRM1TDP1
Hydrochloric Acid SCHEMBL11671229 0.91 SCN5A (0.44) KDM4EALDH1A1TSHRCHRM2CHRM1
SCHEMBL11671963 0.90 PPARG (0.44) KDM4EALDH1A1TSHRCHRM2CHRM1
SCHEMBL11670152 0.90 MTNR1A (0.47) ALDH1A1HTTLMNAMEN1KMT2A
SCHEMBL11670282 0.89 CNR2 (0.42) KDM4EALDH1A1TSHRCHRM2CHRM1
SCHEMBL11702806 0.89 KDM4E (0.40) KDM4EALDH1A1TSHRCHRM2CHRM1
SCHEMBL11672433 0.86 ALDH1A1 (0.41) ALDH1A1TSHRCHRM2CHRM1TDP1
SCHEMBL11670563 0.85 MAOB (0.41) ALDH1A1CHRM2CHRM1TDP1HTT
SCHEMBL11671816 0.85 TSHR (0.43) ALDH1A1TSHRTDP1THRBL3MBTL1
SCHEMBL11671564 0.84 MAPT (0.42) ALDH1A1TSHRCHRM2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4039526-A PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed
US-4039539-A 1,2,4-Triazole-azo-aniline cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed