Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11670526 | 0.82 | MEN1 (0.51) | MEN1KMT2ATSHRMAPTCYP3A4 | |
| SCHEMBL23271325 | 0.79 | RXFP1 (0.49) | MEN1KMT2ARXFP1MAPTALDH1A1 | |
| SCHEMBL11671426 | 0.78 | MEN1 (0.47) | MEN1KMT2ATSHRMAPTCYP3A4 | |
| SCHEMBL11671631 | 0.78 | KMT2A (0.58) | MEN1KMT2ARXFP1MAPTCYP3A4 | |
| SCHEMBL20541420 | 0.75 | NPC1 (0.44) | MEN1KMT2ARXFP1MAPTCYP3A4 | |
| SCHEMBL11671553 | 0.74 | CYP3A4 (0.46) | MEN1KMT2AMAPTCYP3A4NPC1 | |
| SCHEMBL6203162 | 0.73 | ALDH1A1 (0.55) | MEN1KMT2ARXFP1MAPTCYP3A4 | |
| SCHEMBL11673395 | 0.73 | MEN1 (0.51) | MEN1KMT2ATSHRCYP3A4CYP2D6 | |
| SCHEMBL269145 | 0.73 | MEN1 (0.66) | MEN1KMT2ATSHRMAPTCYP3A4 | |
| SCHEMBL11672345 | 0.73 | KMT2A (0.47) | MEN1KMT2AMAPTCYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039526-A | PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |