Sugi Predict

Sugi Predict / Compounds / SCHEMBL269145

SCHEMBL269145

SCHEMBL269145

Cc1ccc(C)c(C(=O)CC(=O)c2ccccc2)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.66
▸ KMT2A Q03164 10/20 0.66
▸ RAB9A P51151 10/20 0.66
▸ NPC1 O15118 8/20 0.66
▸ MAPT P10636 6/20 0.57
▸ KDM4E B2RXH2 5/20 0.57
▸ HPGD P15428 5/20 0.57
▸ SMN1; SMN2 Q16637 5/20 0.57
▸ ALOX15 P16050 2/20 0.57
▸ MAPK1 P28482 2/20 0.57
▸ CYP3A4 P08684 2/20 0.57
▸ CES1 P23141 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ POLB P06746 2/20 0.54
▸ NPSR1 Q6W5P4 4/20 0.54
▸ HTT P42858 3/20 0.54
▸ HSD17B10 Q99714 3/20 0.54
▸ TSHR P16473 1/20 0.54
▸ LMNA P02545 4/20 0.50
▸ KCNH2 Q12809 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7847940 0.94 MEN1 (0.63) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL270726 0.87 KMT2A (0.71) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL7832117 0.85 NPC1 (0.58) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL6762644 0.85 RAB9A (0.73) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL31447540 0.82 MEN1 (0.71) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL29483365 0.82 ERCC5 (0.68) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL269381 0.82 ERCC5 (0.68) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL10932866 0.81 NPC1 (0.64) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL269482 0.80 NPC1 (1.00) MEN1KMT2ARAB9ANPC1MAPT
SCHEMBL305558 0.79 NPSR1 (0.60) MEN1KMT2ANPC1MAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1875 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4395733-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION Unilever IP Holdings B.V. (NL) 2024-07-10 — — EP claimed
US-20240173235-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS MOMENTIVE PERFORMANCE MATERIALS INC. 2024-05-30 — — US claimed
CN-117897133-A Photoprotective personal care compositions 联合利华知识产权控股有限公司 2024-04-16 — — CN claimed
EP-4322915-A1 PERSONAL CARE COMPOSITIONS COMPRISING SILAHYDROCARBONS Momentive Performance Materials Inc. (US) 2024-02-21 — — EP claimed
CN-117425467-A Personal care compositions comprising silicone based 迈图高新材料公司 2024-01-19 — — CN claimed
WO-2023110777-A1 COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A MEROCYANINE AND PENTAERYTHRITYL TETRA-DI-T-BUTYL HYDROXYHYDROCINNAMATE L'OREAL (FR) 2023-06-22 — — WO claimed
WO-2023030963-A1 A PHOTOPROTECTIVE PERSONAL CARE COMPOSITION UNILEVER IP HOLDINGS B.V. (NL) 2023-03-09 — — WO claimed
CN-110831569-B Photoprotective compositions 欧莱雅 2022-10-21 — — CN claimed
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND L'OREAL (FR) 2022-07-21 — — US claimed
CN-114699328-A Photoprotective compositions 欧莱雅 2022-07-05 — — CN claimed
EP-0717982-B1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 1997-07-23 — — EP claimed
EP-0780119-A1 Light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-06-25 — — EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 — — EP claimed
US-5587150-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-12-24 — — US claimed
EP-0748624-A1 Composition containing a dibenzoylmethane derivative and a nanopigment of titanium dioxide and uses thereof L'OREAL (FR) 1996-12-18 — — EP claimed
US-5576354-A Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β,β-diphenylacrylate L'OREAL (FR) 1996-11-19 — — US claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 — — EP claimed
EP-0709080-A1 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1996-05-01 — — EP claimed
EP-0514491-B1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL BETA, BETA-DIPHENYLACRYLATE OR AN ALKYL ALPHA-CYANO-BETA, BETA-DIPHENYLACRYLATE OREAL (FR) 1993-11-03 — — EP claimed
WO-1991011989-A1 LIGHT-RESISTANT FILTERING COSMETIC COMPOSITION CONTAINING A UV-A FILTER AND AN ALKYL β, β-DIPHENYLACRYLATE OR AN ALKYL α-CYANO-β, β-DIPHENYLACRYLATE L'OREAL (FR) 1991-08-22 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220226215-A1 PHOTOPROTECTIVE COMPOSITIONS COMPRISING A DIBENZOYLMETHANE DERIVATIVE, A MEROCYANINE COMPOUND AND A COMPOUND CAPABLE OF ACCEPTING THE TRIPLET EXCITED LEVEL ENERGY OF THE DIBENZOYLMETHANE COMPOUND ERCC5, DDT, ERCC1 MEN1 180/4885KMT2A 3034/4885RAB9A 2771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.