Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11671553 | 0.77 | CYP3A4 (0.46) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11671631 | 0.74 | KMT2A (0.58) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL6203162 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL11672341 | 0.73 | MEN1 (0.54) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL3690329 | 0.71 | RAB9A (0.54) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL24405809 | 0.71 | ALDH1A1 (0.49) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL182321 | 0.70 | ALDH1A1 (0.78) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL269145 | 0.70 | MEN1 (0.66) | KMT2AMEN1RAB9ANPC1ALDH1A1 | |
| SCHEMBL3948272 | 0.70 | NOTUM (0.50) | KMT2AMEN1ALDH1A1KDM4EUSP2 | |
| SCHEMBL11184627 | 0.70 | POLB (0.48) | KMT2AMEN1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039539-A | 1,2,4-Triazole-azo-aniline cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |