Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.79 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | CNR2 | P34972 | 14/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 8/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 5/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726697 | 0.90 | L3MBTL1 (0.79) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11671790 | 0.89 | L3MBTL1 (0.90) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11736681 | 0.89 | L3MBTL1 (0.90) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11673920 | 0.87 | L3MBTL1 (0.92) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11672638 | 0.86 | EYA3 (0.64) | L3MBTL1CYP2C19CNR2CYP2C9 | |
| SCHEMBL11735500 | 0.85 | L3MBTL1 (0.92) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11725573 | 0.83 | L3MBTL1 (0.61) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11724570 | 0.83 | L3MBTL1 (0.88) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11673374 | 0.83 | L3MBTL1 (0.88) | L3MBTL1CYP2C19CNR2ATMCNR1 | |
| SCHEMBL11728474 | 0.83 | L3MBTL1 (0.88) | L3MBTL1CYP2C19CNR2ATMCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4024273-A | Coronary vasodilator and anti-anginal compositions comprising substituted benzofurans and benzothiophenes and methods of producing coronary vasodilation and anti-anginal activity | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-3947470-A | CORONARY VASODILATORS, TREATMENT OF ANGINA PECTORIS | SMITHKLINE CORPORATION (US) | 1976-03-30 | — | — | US | disclosed |