Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | BCHE | P06276 | 8/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11726697 | 0.88 | L3MBTL1 (0.79) | L3MBTL1HPGDCYP2C19CYP2C9BCHE | |
| SCHEMBL11732158 | 0.84 | CYP2C19 (0.57) | L3MBTL1KDM4EHPGDMAPTCYP2C19 | |
| SCHEMBL11673894 | 0.84 | L3MBTL1 (0.69) | L3MBTL1KDM4EHPGDTP53MAPT | |
| SCHEMBL11673096 | 0.83 | L3MBTL1 (0.79) | L3MBTL1MAPTCYP2C19CYP3A4CYP2C9 | |
| SCHEMBL11734945 | 0.82 | APP (0.62) | TP53MAPTTSHRMEN1CYP3A4 | |
| SCHEMBL11729208 | 0.81 | APP (0.69) | BCHEACHECNR2CNR1 | |
| SCHEMBL11728862 | 0.79 | L3MBTL1 (0.57) | L3MBTL1KDM4EHPGDTP53CYP2C19 | |
| SCHEMBL11731169 | 0.79 | ADRB2 (0.52) | MEN1CYP2D6KMT2ABCHEATM | |
| SCHEMBL11673920 | 0.78 | L3MBTL1 (0.92) | L3MBTL1CYP2C19BCHEATMCNR2 | |
| SCHEMBL6586815 | 0.78 | L3MBTL1 (0.73) | L3MBTL1KDM4EHPGDMAPTCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001426-A | HAVING CORONARY VASODILATOR ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |