Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1167387 | 1.00 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL1166981 | 0.75 | TAS2R8 (0.52) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL1168196 | 0.75 | TAS2R8 (0.52) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL1166523 | 0.73 | LMNA (0.44) | SMN1; SMN2LMNAALDH1A1HTTMAPT | |
| SCHEMBL1166162 | 0.67 | TAS2R8 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL1167682 | 0.67 | TAS2R8 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL1166161 | 0.67 | TAS2R8 (0.49) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL1166788 | 0.67 | LMNA (0.57) | LMNAALDH1A1HTTMAPTMEN1 | |
| SCHEMBL1167524 | 0.66 | RAB9A (0.44) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL1166522 | 0.66 | RAB9A (0.44) | SMN1; SMN2LMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | ACTELION (CH) | 2011-02-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034516-A1 | AMINOPYRAZOLE DERIVATIVES | CYP3A43, CYP1A2, CYP3A5 | SMN1; SMN2 4612/4885LMNA 4005/4885ALDH1A1 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.