Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | NSD1 | Q96L73 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.42 |
| ▸ | CEL | P19835 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3902501 | 1.00 | KMO (0.57) | KMOTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13268997 | 0.98 | KMO (0.54) | KMOTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL665155 | 0.91 | TSHR (0.57) | KMOTSHRSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11789159 | 0.87 | KMO (0.43) | KMOPTGDR2PTGDRPTGER2NSD2 | |
| SCHEMBL11674481 | 0.87 | CEL (0.42) | KMOPTGDR2PTGDRPTGER2NSD2 | |
| SCHEMBL6139695 | 0.85 | ALDH1A1 (0.46) | KMOPTGDR2PTGDRCELALDH1A1 | |
| SCHEMBL11675275 | 0.85 | ALDH1A1 (0.46) | KMOPTGDR2PTGDRCELALDH1A1 | |
| SCHEMBL11673685 | 0.85 | SLC6A2 (0.45) | KMOSLC6A4SLC6A2SLC6A3PTGDR2 | |
| SCHEMBL11802460 | 0.83 | CHRNA1 (0.46) | PTGDR2CELMEN1ALDH1A1KMT2A | |
| SCHEMBL15535905 | 0.83 | TSHR (0.45) | KMOTSHRSLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004026-A | Dicarboxylic acids and derivatives in the treatment of pain and inflammation | CIBA-GEIGY CORPORATION (US) | 1977-01-18 | — | — | US | disclosed |
| US-3940434-A | ANTIINFLAMMATORY, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1976-02-24 | — | — | US | disclosed |