Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14503304 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2TSHRALOX15KMT2ANPSR1 | |
| SCHEMBL27339399 | 0.77 | SMN1; SMN2 (0.85) | SMN1; SMN2TSHRALOX15KMT2ANPSR1 | |
| SCHEMBL10839081 | 0.74 | SMN1; SMN2 (0.59) | SMN1; SMN2TSHRALOX15KMT2AKDM4E | |
| SCHEMBL1167505 | 0.73 | HPGD (0.54) | SMN1; SMN2 | |
| SCHEMBL2752062 | 0.72 | TAS1R3 (0.71) | SMN1; SMN2TSHRALOX15TAS1R3TAS1R1 | |
| SCHEMBL21059267 | 0.72 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRALOX15TAS1R3TAS1R1 | |
| SCHEMBL19476103 | 0.72 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRALOX15TAS1R3TAS1R1 | |
| SCHEMBL1030263 | 0.72 | LMNA (0.74) | SMN1; SMN2KMT2AMEN1KDM4ELMNA | |
| SCHEMBL8079340 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2TSHRALOX15KMT2AMEN1 | |
| SCHEMBL20365400 | 0.71 | KMT2A (0.72) | SMN1; SMN2TAS1R3TAS1R1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7893110-B2 | e.g. 1-methyl-cyclohexanecarboxylic acid (3-methoxy-phenyl)-amide; topical products, oral care products, nasal care products, toilet articles, ingestible products and chewing gum | GIVAUDAN S.A. (CH) | 2011-02-22 | — | — | US | disclosed |