SCHEMBL11675183

SCHEMBL11675183

CN(C)C(=O)NC(=N)OC1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.42
NAAA Q02083 2/20 0.36
HTT P42858 2/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
CYP2C19 P33261 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ALDH1A1 P00352 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
CYP19A1 P11511 2/20 0.32
BCHE P06276 1/20 0.32
MEN1 O00255 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11675666 0.82 EPHX1 (0.39) EPHX1NAAAHTTSMN1; SMN2CYP2C19
SCHEMBL3078211 0.79 EPHX1 (0.43) EPHX1NAAAHTTSMN1; SMN2CYP2C19
SCHEMBL11677502 0.77 NAAA (0.46) EPHX1NAAAHTTCA12CA1
SCHEMBL3080031 0.77 EPHX1 (0.44) EPHX1NAAAHTTSMN1; SMN2CYP2C19
SCHEMBL11678640 0.72 ALDH1A1 (0.33) ALDH1A1TSHRHSD17B10MEN1KMT2A
SCHEMBL5622283 0.71 EPHX1 (0.47) EPHX1NAAAHTTSMN1; SMN2CYP2C19
SCHEMBL11679072 0.69 ATM (0.30) MEN1KMT2A
SCHEMBL11675670 0.69 ATM (0.30) MEN1KMT2A
SCHEMBL14759201 0.69 EPHX1 (0.44) EPHX1NAAAHTTCYP2C19CA12
SCHEMBL12298996 0.68 EPHX1 (0.44) EPHX1NAAAHTTSMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4017529-A Herbicidal allophanimidates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed