Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499772 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL109797 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL499467 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL499656 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL500171 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL10951222 | 0.81 | TSHR (0.66) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL110690 | 0.80 | TSHR (0.62) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL4596321 | 0.80 | HDAC1 (0.38) | TSHRTDP1CYP3A4THRBNPSR1 | |
| SCHEMBL7535904 | 0.79 | TSHR (0.65) | TSHRPOLBAPEX1HTTTDP1 | |
| SCHEMBL4919357 | 0.77 | CA2 (0.41) | TSHRTDP1THRBCHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020192-A | AMINO ALKYL AMIDE ACRYLIC POLYMER | FUJI XEROX CO., LTD. (JA) | 1977-04-26 | — | — | US | disclosed |