Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676887 | 0.80 | TSHR (0.31) | HSD17B10TSHR | |
| SCHEMBL11675177 | 0.79 | TSHR (0.32) | TSHR | |
| SCHEMBL11675234 | 0.78 | TET2 (0.47) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL11676492 | 0.77 | FAAH (0.35) | — | |
| SCHEMBL11673131 | 0.77 | GAA (0.45) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL11673893 | 0.77 | RAB9A (0.34) | SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11673971 | 0.77 | POLB (0.33) | — | |
| SCHEMBL11675682 | 0.77 | ALDH1A1 (0.39) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL28596847 | 0.76 | EPHX1 (0.40) | SMN1; SMN2GAAALDH1A1KMT2AKDM4E | |
| SCHEMBL11676560 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017529-A | Herbicidal allophanimidates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |