Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677239 | 0.91 | TSHR (0.44) | TSHRCNR2CNR1MAPT | |
| SCHEMBL11678793 | 0.88 | MAPT (0.42) | TSHRCYP2C19CNR2MAPTPPARG | |
| SCHEMBL11677645 | 0.88 | CNR2 (0.44) | TSHRCNR2CNR1MAPTMAPK1 | |
| SCHEMBL11676210 | 0.87 | PPARG (0.41) | TSHRCNR2CNR1MAPTHTT | |
| SCHEMBL11677277 | 0.87 | PPARG (0.43) | TSHRCNR2CNR1PPARGPPARA | |
| SCHEMBL11676077 | 0.86 | TSHR (0.45) | TSHRCYP2C19CNR2CNR1HTT | |
| SCHEMBL11676749 | 0.85 | MAPT (0.43) | TSHRMAPTHTTTDP1 | |
| SCHEMBL11671807 | 0.80 | MAPT (0.40) | TSHRCNR2CNR1MAPTMAPK1 | |
| SCHEMBL11674550 | 0.79 | NISCH (0.43) | TSHRCNR2MAPK1HTTTDP1 | |
| SCHEMBL11677566 | 0.79 | ALDH1A1 (0.39) | TSHRCNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |