Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677239 | 0.87 | TSHR (0.44) | MAPTTSHR | |
| SCHEMBL11676747 | 0.85 | SLC6A4 (0.42) | MAPT | |
| SCHEMBL11676284 | 0.85 | TSHR (0.40) | MAPTTSHRHTTTDP1 | |
| SCHEMBL11671514 | 0.84 | MAPT (0.43) | MAPTOPRM1OPRD1ACHEHTT | |
| SCHEMBL11670194 | 0.79 | KMT2A (0.39) | MAPTHTTTP53LMNA | |
| SCHEMBL11677645 | 0.79 | CNR2 (0.44) | MAPTTSHRLMNA | |
| SCHEMBL11678793 | 0.79 | MAPT (0.42) | MAPTTSHRACHEPKM | |
| SCHEMBL13791526 | 0.79 | ACHE (0.52) | ACHETDP1LMNA | |
| SCHEMBL11677277 | 0.78 | PPARG (0.43) | TSHRTP53 | |
| SCHEMBL11676210 | 0.78 | PPARG (0.41) | MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |