Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678793 | 0.91 | MAPT (0.42) | TSHRCNR2MAOAMAOBMAPT | |
| SCHEMBL11677645 | 0.91 | CNR2 (0.44) | TSHRCNR2L3MBTL1MAPTALDH1A1 | |
| SCHEMBL11676284 | 0.91 | TSHR (0.40) | TSHRCNR2MAPTCNR1 | |
| SCHEMBL11676210 | 0.90 | PPARG (0.41) | TSHRCNR2MAPTMEN1KMT2A | |
| SCHEMBL11677277 | 0.90 | PPARG (0.43) | TSHRCNR2L3MBTL1MEN1KMT2A | |
| SCHEMBL11676077 | 0.88 | TSHR (0.45) | TSHRCNR2MEN1KMT2ANOX1 | |
| SCHEMBL11676749 | 0.87 | MAPT (0.43) | TSHRMAPT | |
| SCHEMBL11676747 | 0.86 | SLC6A4 (0.42) | MAPTALDH1A1KMT2A | |
| SCHEMBL11677566 | 0.82 | ALDH1A1 (0.39) | TSHRCNR2MAPTALDH1A1MEN1 | |
| SCHEMBL11674550 | 0.81 | NISCH (0.43) | TSHRCNR2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051117-A | Triazole-azo-phenyl cationic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |
| US-4051084-A | BENZOTHIAZOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-27 | — | — | US | disclosed |