SCHEMBL11677449

SCHEMBL11677449

CCN(c1cccc(OC)c1)C(C)Oc1ccccc1Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ABCB1 P08183 4/20 0.42
DRD2 P14416 3/20 0.42
HTR1A P08908 2/20 0.42
DRD1 P21728 1/20 0.41
DRD3 P35462 1/20 0.41
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
ACHE P22303 1/20 0.41
CASR P41180 1/20 0.41
BCHE P06276 1/20 0.41
SLC1A5 Q15758 1/20 0.39
TAAR1 Q96RJ0 3/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP2D6 P10635 2/20 0.38
HTR2A P28223 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11675870 0.88 NPSR1 (0.42) ABCB1DRD2HTR1AACHESLC1A5
SCHEMBL11676135 0.86 DRD1 (0.50) DRD2HTR1ADRD1DRD3MAOB
SCHEMBL11680175 0.86 DRD2 (0.43) DRD2HTR1ADRD1DRD3MAOB
SCHEMBL11671337 0.85 MTNR1B (0.42) SLC1A5
SCHEMBL11675188 0.85 DRD2 (0.42) DRD2DRD1DRD3MAOBMAOA
SCHEMBL11675922 0.84 LTA4H (0.49) MAOBCASRTAAR1CYP2D6
SCHEMBL11676657 0.84 NPSR1 (0.42) ACHETAAR1NPSR1
SCHEMBL11677228 0.83 NPSR1 (0.56) TAAR1NPSR1
SCHEMBL11676858 0.82 TAAR1 (0.46) MAOBCASRTAAR1NPSR1
SCHEMBL11677315 0.81 POLB (0.41) HTR1ADRD3CASRTAAR1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4051084-A BENZOTHIAZOLE BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed
US-4051117-A Triazole-azo-phenyl cationic dyestuffs BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed