Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD17B3 | P37058 | 7/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678301 | 0.90 | L3MBTL1 (0.49) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL10008853 | 0.88 | HSD17B3 (0.57) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL4583779 | 0.87 | HSD17B3 (0.58) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL21610337 | 0.87 | HSD17B3 (0.58) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL2938985 | 0.87 | RAB9A (0.58) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11677381 | 0.86 | RAB9A (0.50) | THRATHRBKDM4EL3MBTL1NPC1 | |
| SCHEMBL11678405 | 0.84 | NPC1 (0.51) | THRATHRBKDM4EL3MBTL1NPC1 | |
| SCHEMBL9597813 | 0.81 | KDM4E (0.64) | KDM4EL3MBTL1NPC1MAPTRAB9A | |
| SCHEMBL11867670 | 0.80 | THRA (0.40) | THRATHRBKDM4EL3MBTL1HSD17B3 | |
| SCHEMBL11780746 | 0.80 | NPC1 (0.53) | THRATHRBKDM4EL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |