Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15791686 | 0.84 | GPR84 (0.43) | GPR84TSHRALDH1A1ATMNPSR1 | |
| SCHEMBL16682975 | 0.83 | GRIN2B (0.38) | IGF1RALOX15S1PR1CDK1 | |
| SCHEMBL4895814 | 0.81 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL30369240 | 0.81 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4900272 | 0.81 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4887234 | 0.81 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL4898274 | 0.81 | HTR2A (0.55) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL22685045 | 0.81 | GRIN2B (0.38) | IGF1RALOX15S1PR1 | |
| SCHEMBL11750577 | 0.81 | HTR2A (0.36) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11801336 | 0.81 | HDAC1 (0.38) | HTR2ADRD2SLC6A2HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3947593-A | ANTIVIRUL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-03-30 | — | — | US | disclosed |