Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678809 | 0.81 | HTR2A (0.38) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11797763 | 0.80 | SIGMAR1 (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL5333274 | 0.78 | CHRM1 (0.42) | HTR2ADRD2SLC6A4MAOAMAOB | |
| SCHEMBL11832433 | 0.77 | KCNH2 (0.44) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11750577 | 0.77 | HTR2A (0.36) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11747299 | 0.77 | IGF1R (0.32) | HDAC1HDAC3HDAC2HDAC6IGF1R | |
| SCHEMBL11797650 | 0.76 | TMEM97 (0.33) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11751988 | 0.76 | SIGMAR1 (0.54) | DRD2SLC6A4TRPV1 | |
| SCHEMBL16682975 | 0.75 | GRIN2B (0.38) | IGF1RALOX15 | |
| SCHEMBL27391726 | 0.75 | GRIN2B (0.38) | IGF1RALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3953602-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-04-27 | — | — | US | disclosed |