Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678809 | 0.81 | HTR2A (0.38) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11862034 | 0.80 | SIGMAR1 (0.47) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| Hydrochloric Acid SCHEMBL11862820 | 0.78 | SIGMAR1 (0.46) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11865232 | 0.77 | SIGMAR1 (0.53) | DRD2SLC6A4 | |
| SCHEMBL11866467 | 0.77 | KCNH2 (0.44) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11801336 | 0.77 | HDAC1 (0.38) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11863353 | 0.76 | PTGS2 (0.33) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11867678 | 0.76 | KCNH2 (0.40) | HTR2ADRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11748974 | 0.76 | SIGMAR1 (0.54) | DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11859118 | 0.76 | KCNH2 (0.43) | HTR2ADRD2SLC6A2HTR2CSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937835-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |