Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679111 | 0.91 | MAPT (0.41) | ALDH1A1POLBMEN1NPC1CYP1A2 | |
| SCHEMBL11682248 | 0.88 | POLB (0.37) | ALDH1A1POLBMEN1NPC1CYP1A2 | |
| SCHEMBL11683739 | 0.86 | RAB9A (0.38) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL10778542 | 0.79 | MAPT (0.38) | ALDH1A1POLBNPC1CYP1A2CYP3A4 | |
| SCHEMBL11389207 | 0.79 | KDM4E (0.46) | ALDH1A1CYP1A2KDM4EHPGDPTPN1 | |
| SCHEMBL11730688 | 0.76 | TP53 (0.44) | ALDH1A1POLBMEN1NPC1CYP1A2 | |
| SCHEMBL10735067 | 0.75 | IRAK4 (0.40) | ALDH1A1POLBMEN1NPC1RAB9A | |
| SCHEMBL11388659 | 0.74 | MEN1 (0.54) | ALDH1A1POLBMEN1KMT2AKDM4E | |
| SCHEMBL10993418 | 0.73 | MAPT (0.41) | ALDH1A1NPC1CYP1A2RAB9AKDM4E | |
| SCHEMBL11740180 | 0.73 | TP53 (0.43) | ALDH1A1POLBKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017625-A | Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor | PFIZER INC. (US) | 1977-04-12 | — | — | US | disclosed |