Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 11/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806168 | 0.88 | ACHE (0.52) | ACHEHTR4CHRM1CHRM2HTR1A | |
| SCHEMBL11678065 | 0.85 | KMT2A (0.67) | KDM4EL3MBTL1CHRM2HTR1AADRA2A | |
| SCHEMBL11750613 | 0.84 | ACHE (0.51) | KDM4EL3MBTL1ACHEHTR4CHRM1 | |
| SCHEMBL11676917 | 0.82 | KDM4E (0.65) | KDM4EL3MBTL1CHRM2HTR1AADRA2A | |
| SCHEMBL11679282 | 0.82 | KDM4E (0.65) | KDM4EL3MBTL1CHRM2HTR1AADRA2A | |
| SCHEMBL11678538 | 0.82 | KDM4E (0.59) | KDM4EL3MBTL1ACHEMCHR1 | |
| SCHEMBL11677718 | 0.81 | KDM4E (0.79) | KDM4EL3MBTL1HTR1ADRD2DRD4 | |
| SCHEMBL11679191 | 0.80 | KDM4E (0.81) | KDM4EL3MBTL1HTR1ADRD2DRD4 | |
| SCHEMBL11678965 | 0.79 | MCHR1 (0.75) | KDM4EL3MBTL1DRD2MCHR1 | |
| Hydrochloric Acid SCHEMBL11676911 | 0.79 | KDM4E (0.79) | KDM4EL3MBTL1HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |