Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.51 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863515 | 0.87 | KMT2A (0.58) | KDM4EL3MBTL1CHRM2HTR1AADRA1A | |
| SCHEMBL11679208 | 0.84 | KDM4E (0.56) | ACHEHTR4KDM4EL3MBTL1CHRM1 | |
| SCHEMBL11868967 | 0.84 | TSHR (0.55) | KDM4EL3MBTL1HRH1HTR1ADRD2 | |
| SCHEMBL11865224 | 0.83 | KDM4E (0.65) | KDM4EL3MBTL1HTR1ADRD2DRD4 | |
| SCHEMBL11748966 | 0.82 | KDM4E (0.67) | KDM4EL3MBTL1KMT2AMCHR1HRH3 | |
| SCHEMBL11806168 | 0.82 | ACHE (0.52) | ACHEHTR4CHRM1HRH1CHRM2 | |
| SCHEMBL11750620 | 0.79 | HRH3 (0.49) | CHRM1CHRM2DRD2CHRM3CHRM4 | |
| SCHEMBL11870369 | 0.79 | KDM4E (0.51) | KDM4EL3MBTL1HRH1HTR1ADRD2 | |
| SCHEMBL11732688 | 0.78 | KDM4E (0.61) | KDM4EL3MBTL1HTR1ADRD2DRD4 | |
| SCHEMBL11859502 | 0.76 | ALDH1A1 (0.62) | KDM4EL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041165-A | TREATING DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937833-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |