Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868967 | 0.88 | TSHR (0.55) | HTR1ADRD3KDM4EL3MBTL1MCHR1 | |
| SCHEMBL11679282 | 0.87 | KDM4E (0.65) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL11750613 | 0.87 | ACHE (0.51) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL11865224 | 0.87 | KDM4E (0.65) | KMT2AHTR1ADRD3HRH3KDM4E | |
| SCHEMBL11748966 | 0.85 | KDM4E (0.67) | KMT2AHRH3KDM4EL3MBTL1MCHR1 | |
| SCHEMBL11678065 | 0.83 | KMT2A (0.67) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| SCHEMBL11870369 | 0.82 | KDM4E (0.51) | HTR1ADRD3KDM4EL3MBTL1MCHR1 | |
| SCHEMBL11732688 | 0.82 | KDM4E (0.61) | KMT2AHTR1ADRD3HRH3KDM4E | |
| SCHEMBL11797618 | 0.80 | KMT2A (0.62) | KMT2AMEN1CHRM2HTR1AADRA2A | |
| Hydrochloric Acid SCHEMBL11871520 | 0.80 | KDM4E (0.59) | KMT2AMEN1HTR1ADRD3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |