Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863524 | 0.86 | SIGMAR1 (0.58) | SIGMAR1HRH3ACHESPHK1HTR7 | |
| SCHEMBL11680152 | 0.83 | SIGMAR1 (0.58) | SIGMAR1HRH3ACHE | |
| SCHEMBL11784879 | 0.83 | SIGMAR1 (0.60) | SIGMAR1HRH3ACHE | |
| Hydrochloric Acid SCHEMBL11678798 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HRH3HTR7 | |
| Hydrochloric Acid SCHEMBL11780956 | 0.82 | SIGMAR1 (0.59) | SIGMAR1HRH3ACHEHTR7 | |
| SCHEMBL11782472 | 0.81 | HRH1 (0.58) | SIGMAR1HRH3 | |
| SCHEMBL11677886 | 0.81 | SIGMAR1 (0.70) | SIGMAR1HRH3 | |
| SCHEMBL11677731 | 0.81 | HTT (0.39) | SIGMAR1 | |
| SCHEMBL11678845 | 0.81 | NPC1 (0.57) | SIGMAR1 | |
| SCHEMBL10538216 | 0.78 | SIGMAR1 (0.61) | SIGMAR1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |
| US-3983124-A | ANTIVIRAL AGENTS | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | disclosed |