Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679286 | 0.81 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL11680152 | 0.79 | SIGMAR1 (0.58) | SIGMAR1DRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11678798 | 0.78 | SIGMAR1 (0.56) | SIGMAR1DRD2SLC6A2HTR2CSLC6A4 | |
| SCHEMBL11782472 | 0.78 | HRH1 (0.58) | SIGMAR1DRD2SLC6A2SLC6A4 | |
| SCHEMBL11678845 | 0.77 | NPC1 (0.57) | HTTSIGMAR1ALDH1A1NPC1TP53 | |
| SCHEMBL11677886 | 0.76 | SIGMAR1 (0.70) | SIGMAR1NAAASLC6A2SLC6A4 | |
| SCHEMBL8091567 | 0.75 | SIGMAR1 (0.62) | SIGMAR1NAAACYP2D6CYP1A2TP53 | |
| SCHEMBL11677726 | 0.74 | KDM4E (0.61) | CYP2D6ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL11677467 | 0.72 | KDM4E (0.56) | CYP2D6ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL11678809 | 0.72 | HTR2A (0.38) | HTR2AALDH1A1NPC1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |