Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550032 | 0.81 | TBXA2R (0.37) | KDM4ERAB9AMAPTNPC1PTGS1 | |
| SCHEMBL11676745 | 0.76 | RAB9A (0.50) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL11678025 | 0.75 | RAB9A (0.49) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL2938985 | 0.73 | RAB9A (0.58) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL11807872 | 0.72 | DPP4 (0.36) | RAB9AMAPTNPC1PTGS1PTGS2 | |
| SCHEMBL10008853 | 0.72 | HSD17B3 (0.57) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL4583779 | 0.71 | HSD17B3 (0.58) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL21610337 | 0.71 | HSD17B3 (0.58) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL11677470 | 0.70 | RAB9A (0.53) | KDM4EL3MBTL1RAB9AMAPTNPC1 | |
| SCHEMBL11678610 | 0.70 | RAB9A (0.53) | KDM4EL3MBTL1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |