Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679296 | 0.81 | KDM4E (0.47) | PTGS1PTGS2HPGDNPC1RAB9A | |
| SCHEMBL11551512 | 0.70 | KDM4E (0.54) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11552376 | 0.70 | TTR (0.43) | STSHPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL11551105 | 0.69 | KDM4E (0.59) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11807872 | 0.69 | DPP4 (0.36) | PTGS1PTGS2HPGDNPC1RAB9A | |
| SCHEMBL11552125 | 0.69 | ALDH1A1 (0.52) | HPGDNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL11551446 | 0.68 | TTR (0.42) | STSNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL11550034 | 0.68 | THRA (0.41) | STSPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL11555272 | 0.67 | TSHR (0.61) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL11748405 | 0.67 | MAOB (0.52) | HPGDALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4146624-A | METHOD OF TREATING VIRUSES WITH BIS-BASIC KETONES OF DIBENZOFURAN | RICHARDSON-MERRELL INC. (US) | 1979-03-27 | — | — | US | disclosed |