Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681952 | 0.90 | HRH3 (0.43) | HRH3KCNH2CCR2SLC6A2HTR1A | |
| SCHEMBL11678119 | 0.86 | HRH3 (0.41) | HRH3KCNH2CCR2SLC6A2MEN1 | |
| SCHEMBL11677590 | 0.85 | HRH3 (0.53) | HRH3KCNH2CCR2SLC6A2HTR1A | |
| SCHEMBL11678752 | 0.83 | SLC6A2 (0.53) | HRH3KCNH2SLC6A2HTR1ACHRM2 | |
| SCHEMBL11681058 | 0.81 | KCNH2 (0.42) | HRH3KCNH2CCR2SLC6A2HTR1A | |
| SCHEMBL11679967 | 0.78 | MTNR1A (0.41) | SLC6A2P2RX1P2RX3P2RX4P2RX7 | |
| SCHEMBL11678564 | 0.77 | SLC6A2 (0.35) | HRH3KCNH2SLC6A2HTR1ACHRM2 | |
| SCHEMBL11680933 | 0.77 | DRD2 (0.39) | HRH3KCNH2SLC6A2HTR1ACHRM2 | |
| SCHEMBL11550207 | 0.77 | HRH3 (0.53) | HRH3KCNH2CCR2SLC6A2HTR1A | |
| SCHEMBL11681955 | 0.76 | DRD2 (0.53) | HRH3KCNH2SLC6A2HTR1ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |