Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | PPIB | P23284 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11678711 | 0.86 | KMT2A (0.47) | NOTUMMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11679967 | 0.85 | MTNR1A (0.41) | PPIBMTNR1AMTNR1BSLC6A2SMN1; SMN2 | |
| SCHEMBL11682308 | 0.83 | PPIB (0.38) | NOTUMPPIBSLC6A2MEN1KMT2A | |
| SCHEMBL11680549 | 0.81 | SLC6A2 (0.53) | SLC6A2MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL11678233 | 0.80 | SIGMAR1 (0.44) | — | |
| SCHEMBL25274049 | 0.80 | PPIB (0.57) | PPIBKMT2ASMN1; SMN2TP53 | |
| SCHEMBL29396441 | 0.80 | PPIB (0.57) | PPIBKMT2ASMN1; SMN2TP53 | |
| SCHEMBL25274050 | 0.80 | PPIB (0.57) | PPIBKMT2ASMN1; SMN2TP53 | |
| SCHEMBL7608772 | 0.80 | ALDH1A1 (0.41) | — | |
| SCHEMBL11678636 | 0.79 | HRH3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017621-A | 2-Morpholinyl tricyclic dibenzazepine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-04-12 | — | — | US | disclosed |