Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | SHBG | P04278 | 5/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 7/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833264 | 0.79 | PGR (0.62) | PGRLMNAESR1SHBGNR3C1 | |
| SCHEMBL8407237 | 0.70 | NR3C1 (0.54) | PGRLMNAESR1NR3C1CYP3A4 | |
| Norgestrienone SCHEMBL146644 | 0.70 | NR3C1 (0.74) | PGRLMNAESR1SHBGNR3C1 | |
| SCHEMBL10495815 | 0.69 | NR3C1 (0.45) | PGRLMNAESR1NR3C1CYP3A4 | |
| SCHEMBL11595243 | 0.66 | CYP19A1 (0.63) | PGRLMNAESR1SHBGNR3C1 | |
| SCHEMBL7858905 | 0.66 | CYP19A1 (0.63) | PGRLMNAESR1SHBGNR3C1 | |
| SCHEMBL13474801 | 0.65 | AR (0.55) | PGRLMNAESR1SHBGNR3C1 | |
| SCHEMBL8408961 | 0.65 | NR3C1 (0.57) | PGRNR3C1AR | |
| SCHEMBL5974395 | 0.65 | PGR (0.59) | PGRLMNAESR1SHBGNR3C1 | |
| Gestadienol SCHEMBL931512 | 0.65 | AR (0.65) | PGRLMNASHBGNR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016270-A | Method for treating dysmenorrhea with a uterine therapeutic system | ALZA CORPORATION (US) | 1977-04-05 | — | — | US | claimed |
| US-4016270-A | Method for treating dysmenorrhea with a uterine therapeutic system | ALZA CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |