SCHEMBL1168086

SCHEMBL1168086

CCN(N=O)C(N)=N[N+](=O)[O-]

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2143726 1.00 ALDH1A1 (0.32) ALDH1A1TP53TSHR
SCHEMBL11478654 0.85 ALDH1A1 (0.30) ALDH1A1TP53
SCHEMBL566952 0.78 ALDH1A1 (0.42) ALDH1A1TP53
SCHEMBL51611 0.78 ALDH1A1 (0.42) ALDH1A1TP53
SCHEMBL8866915 0.78 ALDH1A1 (0.31) ALDH1A1TSHR
SCHEMBL6829129 0.78 ALDH1A1 (0.42) ALDH1A1TP53
SCHEMBL6836619 0.77
SCHEMBL14344854 0.76
SCHEMBL8868248 0.76
SCHEMBL11155134 0.72 CRHBP (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10689644-B2 Systems and methods for genetic analysis of intractable microbes DUKE UNIVERSITY (US) 2020-06-23 US claimed
US-20170306321-A1 SYSTEMS AND METHODS FOR GENETIC ANALYSIS OF INTRACTABLE MICROBES DUKE UNIVERSITY 2017-10-26 US claimed
EP-2342336-B1 CONTINUOUS DIRECTED EVOLUTION OF PROTEINS AND NUCLEIC ACIDS HARVARD COLLEGE (US) 2016-12-14 EP claimed
US-9249088-B2 Continuous production and reaction of a diazo compound DPX HOLDINGS B.V. (NL) 2016-02-02 US claimed
US-20150225752-A1 ACID RESISTANT YEAST CELL AND USE THEREOF SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-08-13 US claimed
EP-2635548-B1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DPX HOLDINGS BV (NL) 2014-12-17 EP claimed
US-20140100360-A1 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) 2014-04-10 US claimed
EP-2635548-A2 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM IP Assets B.V. (NL) 2013-09-11 EP claimed
CN-103189346-A Continuous production and reaction of a diazo compound DSM IP ASSETS BV 2013-07-03 CN claimed
WO-2012059485-A2 CONTINUOUS PRODUCTION AND REACTION OF A DIAZO COMPOUND DSM IP ASSETS B.V. (NL) 2012-05-10 WO claimed
US-7892583-B2 Initiation of fermentation CHR. HANSEN A/S (DK) 2011-02-22 US claimed
EP-1664261-A2 INITIATION OF FERMENTATION Vinobios ApS (DK) 2006-06-07 EP claimed
WO-2004113488-A2 INITIATION OF FERMENTATION VINOBIOS APS (DK) 2004-12-29 WO claimed
US-20260049318-A1 INHIBITION OF PLANT PROTEASE AED3-1 FOR IMPROVED HETEROLOGOUS PROTEIN PRODUCTION UNIV GUELPH (CA) 2026-02-19 US disclosed
WO-2025062150-A1 METHODS OF PRODUCING HOMOPLASMIC MODIFIED PLANTS OR PARTS THEREOF THE UNIVERSITY OF MANCHESTER (GB) 2025-03-27 WO disclosed
US-11992022-B2 Methods and cultures to manufacture pizza cheese INTERNATIONAL N&H DENMARK APS (DK) 2024-05-28 US disclosed
EP-0137010-A4 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES. STANFORD RES INST INT (US) 1985-08-12 EP disclosed
EP-0137010-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES SRI INTERNATIONAL (US) 1985-04-17 EP disclosed
WO-1984003505-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES STANFORD RES INST INT (US) 1984-09-13 WO disclosed
US-4454341-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260049318-A1 INHIBITION OF PLANT PROTEASE AED3-1 FOR IMPROVED HETEROLOGOUS PROTEIN PRODUCTION DPP3, IDE, NOTCH3 ALDH1A1 4141/4885TP53 1352/4885TSHR 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.