SCHEMBL1168133

SCHEMBL1168133

O=C(CO)C[C@@H](O)[C@H](O)CO

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
LMNA P02545 5/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PDE4A P27815 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
OR51E2 Q9H255 1/20 0.35
GABRR1 P24046 2/20 0.31
SLC22A6 Q4U2R8 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20315375 1.00 USP2 (0.41) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL1168135 1.00 USP2 (0.41) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL20518531 1.00 USP2 (0.41) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL21014430 0.83 LMNA (0.50) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL29620322 0.83 LMNA (0.50) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL2480041 0.80 USP2 (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL26092953 0.80 USP2 (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL19383666 0.78 LMNA (0.36) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL6629736 0.77 SLC22A6 (0.50) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL19331126 0.77 SLC22A6 (0.50) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111638363-B 3-deoxyfructose rapid quantitative fluorescence detection device and preparation method thereof 吉林省格瑞斯特生物技术有限公司 2022-02-18 CN claimed
CN-111638363-A 3-deoxyfructose rapid quantitative fluorescence detection device and preparation method thereof 吉林省格瑞斯特生物技术有限公司 2020-09-08 CN claimed
CN-108902304-A A kind of the brown fermented milk beverage and its processing method of low 3- deoxyfructose and 5 hydroxymethyl furfural content 南开大学 2018-11-30 CN claimed
JP-4738554-B2 2011-08-03 JP claimed
CN-1919201-A Compounds and methods for therapeutic intervention in preventing diabetic complications FOX CHASE CANCER CT (US) 2007-02-28 CN claimed
CN-1148185-C Inhibitor for generation of 3-deoxyglucurone �ձ���ҩ��ʽ���� 2004-05-05 CN claimed
EP-1085885-B1 METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION FOX CHASE CANCER CT (US) 2003-10-01 EP claimed
EP-1021175-A4 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CT (US) 2002-08-28 EP claimed
JP-2001512424-A 2001-08-21 JP claimed
EP-1021175-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 2000-07-26 EP claimed
CN-1251521-A Compounds and methods for therapeutic intervention in preventing diabetic complications FOX CHASE CANCER CENTER (US) 2000-04-26 CN claimed
WO-1998033492-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 1998-08-06 WO claimed
CN-1185948-A Inhibitor for generation of 3-deoxyglucurone NIPPON ZOKI PHARMACEUTICAL CO (JP) 1998-07-01 CN claimed
EP-3778580-B1 SYNTHESIS OF FURANS FROM SUGARS VIA KETO INTERMEDIATES BP CORP NORTH AMERICA INC (US) 2025-12-17 EP disclosed
US-11981888-B2 Synthesis of furans from sugars via keto intermediates BP CORPORATION NORTH AMERICA INC. (US) 2024-05-14 US disclosed
US-11957728-B2 Compositions for targeting receptor for advanced glycation end-products (RAGE) in a chronic inflammatory condition SAMI-SABINSA GROUP LIMITED (IN) 2024-04-16 US disclosed
WO-1999064561-A2 METHOD FOR ASSESSING A DIABETIC'S RISK OF EXPERIENCING A DIABETES-ASSOCIATED PATHOLOGIC CONDITION FOX CHASE CANCER CENTER (US) 1999-12-16 WO disclosed
WO-1998033492-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 1998-08-06 WO disclosed
WO-1998033492-A1 COMPOUNDS AND METHODS FOR THERAPEUTIC INTERVENTION IN PREVENTING DIABETIC COMPLICATIONS FOX CHASE CANCER CENTER (US) 1998-08-06 WO disclosed
CN-1185948-A Inhibitor for generation of 3-deoxyglucurone NIPPON ZOKI PHARMACEUTICAL CO (JP) 1998-07-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11981888-B2 Synthesis of furans from sugars via keto intermediates HPD, KHK, ALDOA USP2 2160/4885SLCO1B1 259/4885LMNA 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.