SCHEMBL2480041

SCHEMBL2480041

NC(=O)C[C@H](O)[C@H](O)CO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
LMNA P02545 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PDE4A P27815 1/20 0.37
TDP1 Q9NUW8 2/20 0.36
OR51E2 Q9H255 1/20 0.33
KDM4E B2RXH2 1/20 0.32
GMNN O75496 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
GLA P06280 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
THPO P40225 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26092953 1.00 USP2 (0.39) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL7383379 0.88 LMNA (0.39) USP2LMNAL3MBTL1TDP1OR51E2
SCHEMBL15754347 0.84 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL7510580 0.84 LMNA (0.55) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL599666 0.84 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL26091297 0.84 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL3851276 0.84 LMNA (0.48) USP2SLCO1B1LMNAL3MBTL1PDE4A
Hydrochloric Acid SCHEMBL28610464 0.82 LMNA (0.46) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL20315375 0.80 USP2 (0.41) USP2SLCO1B1LMNAL3MBTL1PDE4A
SCHEMBL20518531 0.80 USP2 (0.41) USP2SLCO1B1LMNAL3MBTL1PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2376087-A1 ERBB-3 (HER3)-SELECTIVE COMBINATION THERAPY Santaris Pharma A/S (DK) 2011-10-19 EP claimed
CN-102223886-A Erbb-3 (her3)-selective combination therapy ENZON PHARMACEUTICALS INC 2011-10-19 CN claimed
WO-2010054051-A1 ERBB-3 (HER3)-SELECTIVE COMBINATION THERAPY SANTARIS PHARMA A/S (DK) 2010-05-14 WO claimed
US-5045338-A Ester imides, acylated aminoalcohol derivatives NABISCO BRANDS, INC. (US) 1991-09-03 US claimed
EP-4658408-A2 RESPIRATORY BIOMARKER PANEL Cepheid (US) 2025-12-10 EP disclosed
EP-4526479-A1 MVP CARTRIDGE AND METHODS OF USE AND MANUFACTURE Cepheid (US) 2025-03-26 EP disclosed
WO-2024163366-A9 RESPIRATORY BIOMARKER PANEL CEPHEID (US) 2025-02-20 WO disclosed
WO-2024163366-A2 RESPIRATORY BIOMARKER PANEL CEPHEID (US) 2024-08-08 WO disclosed
CN-117106887-A Compositions and methods for diagnosing and treating tuberculosis 塞弗德公司 2023-11-24 CN disclosed
WO-2023225362-A1 MVP CARTRIDGE AND METHODS OF USE AND MANUFACTURE CEPHEID (US) 2023-11-23 WO disclosed
CN-116635538-A Compositions and methods for diagnosing and treating tuberculosis 塞弗德公司 2023-08-22 CN disclosed
CN-116348767-A Method for diagnosing tuberculosis and distinguishing active tuberculosis from latent tuberculosis 西菲伊德公司 2023-06-27 CN disclosed
WO-2023070123-A1 COMPOSITIONS AND METHODS OF DIAGNOSING AND TREATING TUBERCULOSIS CEPHEID (US) 2023-04-27 WO disclosed
CN-105209634-B Enzyme arrest method 牛津纳米孔技术公司 2020-05-12 CN disclosed
US-7393954-B2 Process for the production of pentostatin aglycone and pentostatin RELIABLE BIOPHARMACEUTICAL CORPORATION (US) 2008-07-01 US disclosed
US-20040181052-A1 Process for the production of pentostatin aglycone and pentostatin APPLIED SILICONE COMPANY LLC 2004-09-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040181052-A1 Process for the production of pentostatin aglycone and pentostatin DTYMK, RNGTT, DDOST USP2 3600/4885SLCO1B1 4318/4885LMNA 3343/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.