Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11680118 | 0.88 | SREBF1 (0.42) | ALDH1A1TSHRKMT2AMEN1LMNA | |
| SCHEMBL11684709 | 0.86 | PGR (0.49) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL11657083 | 0.80 | ALDH1A1 (0.47) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| Methane SCHEMBL11681369 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL11682666 | 0.77 | KDM4E (0.45) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| Methane SCHEMBL11682364 | 0.76 | KDM4E (0.44) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL11684030 | 0.75 | KMT2A (0.51) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL11680630 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TSHRKMT2AMEN1KDM4E | |
| SCHEMBL11682345 | 0.73 | KDM4E (0.43) | ALDH1A1GLAKMT2AMEN1KDM4E | |
| SCHEMBL11686057 | 0.72 | PGR (0.51) | ALDH1A1KMT2AMEN1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |