Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11682364 | 0.99 | KDM4E (0.44) | KDM4EALDH1A1MCOLN3HSD17B1HSD17B2 | |
| SCHEMBL11657083 | 0.86 | ALDH1A1 (0.47) | KDM4EALDH1A1MCOLN3TSHRHSD17B10 | |
| SCHEMBL11683316 | 0.85 | ALDH1A1 (0.48) | KDM4EALDH1A1MCOLN3HSD17B1HSD17B2 | |
| Methane SCHEMBL11681369 | 0.85 | ALDH1A1 (0.46) | KDM4EALDH1A1MCOLN3TSHRHSD17B10 | |
| SCHEMBL11682345 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1MCOLN3HSD17B1HSD17B2 | |
| SCHEMBL11685618 | 0.81 | ALDH1A1 (0.43) | KDM4EALDH1A1MCOLN3TSHRHSD17B10 | |
| SCHEMBL11684642 | 0.81 | HSD17B1 (0.47) | KDM4EALDH1A1MCOLN3HSD17B1HSD17B2 | |
| SCHEMBL11680630 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1MCOLN3TSHRHSD17B10 | |
| SCHEMBL11681883 | 0.77 | ALDH1A1 (0.41) | KDM4EALDH1A1TSHRTDP1MAPT | |
| SCHEMBL11684709 | 0.75 | PGR (0.49) | KDM4EALDH1A1MCOLN3HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |