Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2603075 | 0.79 | ESR1 (0.71) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL11683080 | 0.77 | LMNA (0.41) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| Methane SCHEMBL11680886 | 0.75 | ESR1 (0.62) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL30010872 | 0.72 | ALDH1A1 (0.43) | HSD17B10TSHRALDH1A1LMNAACHE | |
| SCHEMBL6297046 | 0.70 | ESR1 (0.62) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL11441700 | 0.70 | HSD17B10 (0.44) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL6297282 | 0.70 | ESR1 (0.70) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL5467499 | 0.70 | ESR1 (0.58) | ESR1HSD17B10KMT2ATSHRMAPK1 | |
| SCHEMBL30009960 | 0.70 | TSHR (0.41) | TSHRMAPK1ALDH1A1MAPTLMNA | |
| SCHEMBL11686420 | 0.69 | ESR1 (0.46) | ESR1HSD17B10TSHRRORCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |