Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5464725 | 0.85 | ALDH1A1 (0.58) | ESR1ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL879153 | 0.76 | CA1 (0.68) | ALDH1A1HPGDHSD17B10ALOX15LMNA | |
| SCHEMBL31208448 | 0.76 | CA1 (0.68) | ALDH1A1HPGDHSD17B10ALOX15LMNA | |
| SCHEMBL14469869 | 0.75 | RORC (0.45) | ESR1ALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL5467456 | 0.75 | ALDH1A1 (0.60) | ESR1ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL10693591 | 0.73 | ALDH1A1 (0.60) | ALDH1A1LMNATSHRSMN1; SMN2MAPT | |
| SCHEMBL11686703 | 0.73 | ACLY (0.46) | ESR1ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11684564 | 0.73 | CA12 (0.49) | ALDH1A1HPGDHSD17B10ALOX15TSHR | |
| SCHEMBL11684642 | 0.71 | HSD17B1 (0.47) | ALDH1A1HSD17B10LMNATSHRSMN1; SMN2 | |
| SCHEMBL11682666 | 0.71 | KDM4E (0.45) | ALDH1A1HSD17B10LMNATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |