Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE1A | P54750 | 1/20 | 0.45 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.45 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.41 |
| ▸ | MERTK | Q12866 | 1/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | FER | P16591 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689307 | 0.88 | KDM4E (0.37) | PDE1APDE1BPDE1CKMT2ACMKLR1 | |
| SCHEMBL11681768 | 0.83 | KHK (0.47) | KMT2ADCLK1PRKD3MAP4K4CHEK2 | |
| SCHEMBL11687173 | 0.79 | RET (0.44) | PDE1APDE1BPDE1CKMT2ACMKLR1 | |
| SCHEMBL11683265 | 0.77 | KDM4E (0.46) | PDE1APDE1BPDE1CKMT2ACMKLR1 | |
| SCHEMBL11681765 | 0.76 | CASR (0.49) | PDE1APDE1BPDE1CCMKLR1KDM4E | |
| SCHEMBL11686272 | 0.71 | DCLK1 (0.71) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL11683676 | 0.70 | DHODH (0.39) | KMT2AKDM4EMAPTMEN1 | |
| SCHEMBL11688810 | 0.70 | KHK (0.44) | DCLK1PRKD3MAP4K4CHEK2CSF1R | |
| SCHEMBL23219249 | 0.69 | KDM4E (0.39) | KMT2ACMKLR1KDM4ECASRMAPT | |
| SCHEMBL4499277 | 0.69 | L3MBTL1 (0.59) | KMT2ADCLK1PRKD3MAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |