Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 3/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11689307 | 0.86 | KDM4E (0.37) | KDM4EPDE1APDE1BPDE1CMAPT | |
| SCHEMBL11681765 | 0.85 | CASR (0.49) | KDM4EPDE1APDE1BPDE1CMAPT | |
| SCHEMBL11687173 | 0.84 | RET (0.44) | KDM4EPDE1APDE1BPDE1CSRC | |
| SCHEMBL11682150 | 0.81 | KHK (0.44) | KDM4EMAPTLMNAKMT2AGAA | |
| SCHEMBL11681541 | 0.78 | NR1H3 (0.47) | KDM4EMAPTLMNAPIK3CDPRKDC | |
| SCHEMBL11683155 | 0.77 | PDE1A (0.45) | KDM4EPDE1APDE1BPDE1CMAPT | |
| SCHEMBL11682571 | 0.76 | ESR1 (0.46) | KDM4EMAPTLMNAKMT2AMEN1 | |
| SCHEMBL13324089 | 0.74 | NPSR1 (0.59) | MAPTLMNAKMT2AMEN1GAA | |
| SCHEMBL11685049 | 0.72 | PRKDC (0.43) | KDM4EMAPTLMNAPIK3CDPIK3CA | |
| SCHEMBL9923853 | 0.72 | KMT2A (0.47) | KDM4EPDE1APDE1BPDE1CSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |