Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681541 | 0.89 | NR1H3 (0.47) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL11682150 | 0.82 | KHK (0.44) | MAPTTP53KMT2AKDM4EALDH1A1 | |
| SCHEMBL11685049 | 0.81 | PRKDC (0.43) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11685644 | 0.81 | PIK3CD (0.46) | ESR1MAPTTP53MEN1KMT2A | |
| SCHEMBL11683265 | 0.76 | KDM4E (0.46) | MAPTMEN1KMT2AKDM4ETSHR | |
| SCHEMBL11684444 | 0.75 | KDM4E (0.46) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL11835478 | 0.70 | MAPT (0.59) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11688645 | 0.69 | L3MBTL1 (0.55) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11846094 | 0.69 | MAPT (0.58) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4032520 | 0.69 | ESR1 (0.60) | ESR1MAPTTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |