Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681541 | 0.83 | NR1H3 (0.47) | PRKDCPIK3CDMAPTALDH1A1NPSR1 | |
| SCHEMBL11682571 | 0.81 | ESR1 (0.46) | MAPTALDH1A1NPSR1LMNACYP1A2 | |
| SCHEMBL11685644 | 0.80 | PIK3CD (0.46) | PRKDCPIK3CDMAPTALDH1A1NPSR1 | |
| SCHEMBL11682150 | 0.75 | KHK (0.44) | MAPTALDH1A1NPSR1LMNAKMT2A | |
| SCHEMBL11683265 | 0.72 | KDM4E (0.46) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL11684444 | 0.68 | KDM4E (0.46) | MAPTALDH1A1NPSR1LMNAHPGD | |
| SCHEMBL11685205 | 0.65 | MAP2K4 (0.50) | MAPTALDH1A1NPSR1LMNACYP1A2 | |
| SCHEMBL11640838 | 0.65 | MAPT (0.58) | MAPTALDH1A1NPSR1LMNAHPGD | |
| SCHEMBL13019688 | 0.63 | PIK3CD (0.68) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2982125 | 0.63 | PTGER4 (0.49) | MAPTALDH1A1NPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |