Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686263 | 0.90 | TSHR (0.51) | LMNAPOLBTRPV1EPHX2TSHR | |
| SCHEMBL9687321 | 0.82 | LMNA (0.54) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL11000662 | 0.82 | EPHX2 (0.67) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL11684069 | 0.81 | LMNA (0.52) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL11682241 | 0.80 | TSHR (0.53) | TRPV1EPHX2TSHR | |
| SCHEMBL11684086 | 0.80 | EPHX2 (0.55) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL10671063 | 0.80 | TRPV1 (0.58) | TRPV1EPHX2ALDH1A1TSHR | |
| SCHEMBL11681677 | 0.78 | EPHX2 (0.57) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL11686688 | 0.78 | EPHX2 (0.53) | LMNAPOLBTRPV1EPHX2ALDH1A1 | |
| SCHEMBL10592956 | 0.77 | ALDH1A1 (0.49) | LMNAPOLBTRPV1EPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |