Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683333 | 0.90 | LMNA (0.50) | TSHRLMNAPOLBTRPV1EPHX2 | |
| SCHEMBL11682241 | 0.90 | TSHR (0.53) | TSHRTRPV1EPHX2APEX1TP53 | |
| SCHEMBL10671063 | 0.90 | TRPV1 (0.58) | TSHRTRPV1EPHX2TP53CA12 | |
| SCHEMBL11683842 | 0.86 | TSHR (0.56) | TSHRTRPV1EPHX2APEX1TP53 | |
| SCHEMBL11684390 | 0.85 | LMNA (0.72) | LMNAPOLBEPHX2TP53 | |
| SCHEMBL9687321 | 0.84 | LMNA (0.54) | LMNAPOLBTRPV1EPHX2CA1 | |
| SCHEMBL11845089 | 0.83 | EPHX2 (0.67) | TSHRTRPV1EPHX2 | |
| SCHEMBL11000662 | 0.83 | EPHX2 (0.67) | LMNAPOLBTRPV1EPHX2TP53 | |
| SCHEMBL11684069 | 0.82 | LMNA (0.52) | TSHRLMNAPOLBTRPV1EPHX2 | |
| SCHEMBL11686688 | 0.82 | EPHX2 (0.53) | LMNAPOLBTRPV1EPHX2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |