Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.44 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662764 | 0.84 | HPGD (0.47) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL1476946 | 0.78 | SMN1; SMN2 (0.61) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL11592277 | 0.76 | MAOB (0.58) | KMT2AMEN1MAPTPOLBGAA | |
| SCHEMBL14328976 | 0.76 | MAPT (0.50) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL23640265 | 0.74 | HSP90AA1 (0.54) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL13603962 | 0.74 | TP53 (0.61) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL25336401 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5512049 | 0.73 | ALDH1A1 (0.47) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL5551757 | 0.73 | MAPT (0.47) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL27704241 | 0.72 | MAPT (0.51) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4046752-A | Process for preparing an azo compound from a 2-aminothiazole diazo component | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-09-06 | — | — | US | disclosed |
| US-3947515-A | Process for the preparation of pure, aromatic o-hydroxy-carboxylic acid aryl amides | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-03-30 | — | — | US | disclosed |