Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682851 | 0.81 | NPC1 (0.46) | MAPTALDH1A1NPC1RAB9ANR4A2 | |
| SCHEMBL11685986 | 0.79 | ADORA3 (0.40) | MAPTALDH1A1NPC1RAB9ANR4A2 | |
| SCHEMBL11683967 | 0.71 | NR4A2 (0.41) | MAPTSMN1; SMN2HSD17B10NR4A2PARP1 | |
| SCHEMBL3325636 | 0.69 | PDE2A (0.50) | MAPTALDH1A1RAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL9919058 | 0.66 | L3MBTL1 (0.59) | ALDH1A1HSD17B10PARP1MEN1KMT2A | |
| SCHEMBL24754380 | 0.66 | PARP1 (0.44) | NPC1RAB9ANR4A2PARP1HTT | |
| SCHEMBL827782 | 0.64 | NR4A2 (0.61) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12844378 | 0.64 | CSF1R (0.51) | ALDH1A1NR4A2PARP1HTTMEN1 | |
| SCHEMBL405936 | 0.64 | DPP4 (0.47) | NR4A2PARP1 | |
| SCHEMBL26690566 | 0.64 | RXFP1 (0.69) | SMN1; SMN2HSD17B10POLBMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020083-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1977-04-26 | — | — | US | disclosed |