Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682851 | 0.89 | NPC1 (0.46) | ADORA3GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL11683695 | 0.79 | MAPT (0.53) | HTTNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9265085 | 0.67 | MAPT (0.44) | ADORA3RAB9AALDH1A1MAPT | |
| SCHEMBL4413557 | 0.66 | KDM4E (0.48) | ADORA3ALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11683967 | 0.66 | NR4A2 (0.41) | MAPTNR4A2 | |
| SCHEMBL14189315 | 0.65 | MPO (0.49) | ADORA3ALDH1A1MAPTTSHRGAA | |
| SCHEMBL24754381 | 0.64 | DDR1 (0.54) | RAB9A | |
| SCHEMBL4416515 | 0.64 | KDM4E (0.43) | ADORA3ALDH1A1MAPTTSHRGAA | |
| SCHEMBL6717022 | 0.63 | ADORA3 (0.87) | ADORA3 | |
| SCHEMBL17674851 | 0.63 | KCNH2 (0.36) | TLR8GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4020083-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1977-04-26 | — | — | US | disclosed |