Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP2 | Q9HC62 | 7/20 | 0.51 |
| ▸ | SUMO2 | P61956 | 5/20 | 0.51 |
| ▸ | SUMO1 | P63165 | 5/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 5/20 | 0.51 |
| ▸ | ATIC | P31939 | 3/20 | 0.51 |
| ▸ | SENP1 | Q9P0U3 | 6/20 | 0.47 |
| ▸ | SENP3 | Q9H4L4 | 4/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177949 | 0.90 | SENP2 (0.51) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL15274161 | 0.84 | SENP2 (0.58) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL12177915 | 0.83 | ATIC (0.61) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL15121150 | 0.83 | SENP2 (0.58) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL28564381 | 0.83 | SENP2 (0.54) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL9179509 | 0.83 | SENP2 (0.50) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL15274136 | 0.82 | SENP2 (0.60) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL12177923 | 0.81 | ATIC (0.47) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL13722703 | 0.81 | SENP2 (0.66) | SENP2SUMO2SUMO1SENP7ATIC | |
| SCHEMBL15274152 | 0.81 | SENP3 (0.56) | SENP2SUMO2SUMO1SENP7ATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4001205-A | WATER-SOLUBLE, FIBER-REACTIVE PHENYLAZODIHYDROXY, METHYL, CYANOPYRIDINE DYESTUFFS | CIBA-GEIGY AG (CH) | 1977-01-04 | — | — | US | disclosed |
| US-3956263-A | 4-Methyl-2,6-dihydroxy-3-cyanopyridine containing dyestuffs | CIBA-GEIGY AG (CH) | 1976-05-11 | — | — | US | disclosed |