Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 3/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682971 | 0.91 | KMT2A (0.43) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL11683424 | 0.88 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL11679777 | 0.85 | MEN1 (0.46) | MEN1KMT2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL11680102 | 0.85 | AKR1C3 (0.45) | AKR1C3AKR1C2ALDH1A1KDM4ETDP1 | |
| SCHEMBL11680895 | 0.82 | AKR1C3 (0.43) | MEN1KMT2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL11680546 | 0.82 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL11683356 | 0.81 | RAB9A (0.43) | MEN1KMT2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL11683366 | 0.81 | RAB9A (0.43) | MEN1KMT2AAKR1C3AKR1C2ALDH1A1 | |
| SCHEMBL6023191 | 0.81 | AKR1C3 (0.47) | AKR1C3AKR1C2ALDH1A1KDM4ETDP1 | |
| SCHEMBL6023193 | 0.81 | AKR1C3 (0.47) | AKR1C3AKR1C2ALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016193-A | ANALGESICS, ANTIINFLAMMATORY AGENTS | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JA) | 1977-04-05 | — | — | US | disclosed |